Use when invalid data causes failures deep in execution, requiring validation at multiple system layers - validates at every layer data passes through to make bugs structurally impossible
Quick integration into your workflow with minimal setup
Active open-source community with continuous updates
MIT/Apache licensed for commercial and personal use
Customizable and extendable based on your needs
Download or copy the skill file from the source repository
Place the skill file in Claude's skills directory (usually ~/.claude/skills/）。
Restart Claude or run the reload command to load the skill
Tip: Read the documentation and code carefully before first use to understand functionality and permission requirements
All Skills from open-source community, preserving original authors' copyrights
obra__superpowers/skills/defense-in-depth/skill.mdProven benefits and measurable impact
Instantly access SNP-trait data without manual database searches.
Minimize human error in variant lookups with automated queries.
Skip hours of manual catalog browsing for comprehensive results.
Perfect for these scenarios
Calculate PRS by retrieving SNP-trait associations for multiple variants.
Identify disease associations for a specific rs ID in the GWAS Catalog.
Search all known SNPs linked to a specific disease or trait.
Explore variants near a gene to find significant trait associations.